Autologous hematopoietic stem cell transplantation (HSCT) is a regenerative medicine therapy option used to reboot the immune system. The process entails the transplantation of multipotent hematopoietic stem cells, typically from bone marrow, cord blood, or peripheral blood. The therapy is gaining awareness as a treatment for multiple sclerosis (MS), as its aim is to reset the immune system, which causes the brain and spinal damage seen in the condition. If you’re exploring HSCT for MS, here are a few must-known facts:
How does HSCT for MS work?
In addition to modulating the immune system, HSCT can also curb inflammation, a key contributor to MS. With their immune regulating properties, stem cells can prevent the immune system from attacking the myelin sheath and may even aid in its regeneration.
Who might be a good candidate for HSCT?
People with highly inflammatory relapsing-remitting MS appear to benefit from HSCT, according to studies. This includes patients who can walk, have been diagnosed with MS 10 years ago or fewer, and have had little to no success with other therapies.
What have studies shown about HSCT?
Studies on HSCT for MS have all used unique treatment regimens and criteria, so a definitive analysis is difficult to achieve at this point. Factors such as the patients’ individual symptoms and the intensity of treatment can affect variations in outcomes. With that being said, results have been promising. Some patients have experienced long stretches of remission, and in certain cases, key functionalities which had been lost have even been restored. The treatment has also been shown to outperform other conventional therapies for MS.
Where is HSCT for MS available?
Several clinical trials for HSCT for MS are currently underway, with more being expected to begin throughout the U.S. At centers where stem cell therapy is offered for autoimmune disease, the treatment may also be offered to patients with MS. Of course, it’s important to make sure that the center you choose is experienced in treating neurodegenerative conditions.
This post was written by Becky Palmer, a medical professional at Stemedix Inc. At Stemedix we offer Regenerative Medicine, also known as Stem Cell Therapy in Tampa, this therapy naturally acts to rebuild and regenerate neural tissues that are lost from the progression of all different types of diseases.